The system includes a mass spectrometer, a turbo v ion source, a computer, and the analyst software. Ametek proline mass spectrometer user manual process instruments 150 freeport road 90516ve, rev zb pittsburgh, pa 15238. Compounds introduced into the spectrometer produce a characteristic mass spectrum which can be used to obtain. Perkinelmers nexion 2000 is the most versatile icpms on the market, featuring an array of unique technologies that combine to deliver the highest performance no matter what your analytical challenge. In this process, the program finds all nucleotide combinations that, if combined as a single oligomer, would fall within the total mass range. The quadrupole rod assembly operates as ion transmission device with the.
Profile data is the data generated by the mass spectrometer and corresponds to the intensity recorded at a series of evenly spaced discrete mass values. With the aid of fieldaxis technology, the ions are able to cross the peripheral fields of the separating system. Designed to bring the benefits of ms chemical analysis to the field, the portability tm can service a variety of bulk or trace detection applications with its compact form factor and intuitive user software. The hardware descriptions in this manual revision refer to the isq ec mass spectrometer. The tsq quantum ultra is a member of the tsq family of finnigan mass spectrometers. The maldi8020 is the latest in a long line of malditof products from shimadzu. Finnigan tsq quantum ultra thermo fisher scientific. Make offer agilent 6210 lcms tof mother pca for mass spectrometer g196960012 rev b 6200 agilent g1978a60803 rev. Ion chromatography mass spectrometry icms employ icms when you need to increase your ic detection capability, such as to detect and quantify unexpected coelutions or confirm trace components. Hesi is especially useful for the mass analysis of polar compounds, which include biological polymers for example, proteins, peptides. May 26, 2015 this target total mass is then used to calculate potential nucleotide compositions. Mass spectrometry, also called mass spectroscopy, analytic technique by which chemical substances are identified by the sorting of gaseous ions in electric and magnetic fields according to. This benchtop, linear malditof mass spectrometer delivers outstanding performance in a compact footprint, making it an ideal choice for todays increasingly demanding laboratories. This enables a high level of sensitivity ahpa to be achieved without the need for pre and post filters.
The maxis mass spectrometer uses very high voltages. What is the agilent triple quadrupole mass spectrometer. Worldleading combination of mass accuracy, resolution, and sensitivity smartformula is the unique combination of accurate mass with true isotopic pattern tip automated determination of elemental. Isq ec and isq em mass spectrometer operating manual. Epr spectrometer users manual institute of molecular. Page 119 clarus 600680 users guide setting the timed events 1. Chems the chems user interface simplifies the mass spectrometry experience and makes it more accessible in chemistry and biochemistry laboratories. Malditof mass spectrometry, toftof, maldi8020, maldi. Under normal operation, the instrument requires no user access to the inner components of the instrument. The user interface allows users to quickly select the workflow and type of compound they wish to analyze in just a few clicks of the mouse and the software automatically optimizes the ion source and.
See the gc and autosampler user manuals for instructions on injecting samples. Epr spectrometer users manual basic operations e 500. In addition to this manual, thermo fisher scientific provides other documents for the exactive plus mass spectrometer that are not part of the original operating. For example, for a mass range 100 da to 200 da and step size 0. Tsq 8000 evo laboratory equipment pdf manual download. Vs series helium operation manual mass spectrometer.
Portable mass spec bayspec high performance spectrometers. Industrial safety analysis for flare gas and ambient air monitoring. This benchtop, linear malditof mass spectrometer delivers outstanding performance in a compact footprint, making it an. In this process, the program finds all nucleotide combinations that, if combined as a single oligomer, would. Our wide range of powerful, versatile, and proven mass spectrometrybased solutions deliver a new level of understanding and control in vacuum and gasrelated applications to customers. A quadrupole mass spectrometer skoog, holler, and crouch, 2007 the quadrupole mass spectrometer figure 6 is the most common type of mass spectrometer used in atomic mass spectroscopy. Ensure that the mass spectrometer software is closed. Adaptable for a multitude of reagent ions, including. Vs series helium operation manual mass spectrometer leak. Selective detection based on the employed reagent ion chemistry. When using a mass spectrometer, you would not want the initial pressure to be too high, because at the end of the gc run all parameters are set back to their initial values, and the higher pressure could cause damage to the vacuum system. Chemical ionization timeofflight mass spectrometer tofcims the aerodyne tofcims combines chemical ionization with highresolution timeofflight mass spectrometry for sensitive, realtime. Finnigan mat252 with kiel iii carbonate device i operation principles for.
This manual also contains safety messages, precautionary statements, and special notices that can prevent personal injury, damage to the detector, or loss of. About this guide this exactive operating manual describes the modes of operation and principle hardware. Mar 24, 2020 mass spectrometry, analytic technique by which chemical substances are identified by the sorting of gaseous ions in electric and magnetic fields according to their mass tocharge ratios. Inductively coupled plasma mass spectrometry icpms identify and characterize organic and inorganic samples at ppm to subppt levels. Extrel realtime gas analyzers for research and industry. A computer is used to control the mass spectrometer and for processing the data. Q exactive hybrid quadrupoleorbitrap ms with zipchip system a comprehensive ceesims solution for biopharma applications.
Researchquality, highperformance system in an educational package. Ltq orbitrap series preinstallation requirements guide orbitrap velos pro getting started guide velos pro manual set you can access pdf files of the docume nts listed above an d of this guide from the data system computer. This target total mass is then used to calculate potential nucleotide compositions. Q exactive hybrid quadrupole orbitrap mass spectrometer. The microflex ltsh malditof mass spectrometer with n 2 laser at 60 hz repetition rate the microflex ltsh smart system with brukers proprietary smartbeam solidstate laser technology at. Orbitrap idx tribrid mass spectrometer thermo fisher. Four parallel cylindrical rods serve as electrodes. In this manual this manual describes the operation, troubleshooting, and maintenance of the agilent technologies 5973 network mass selective detector 5973n msd 1069huvlrq 5973n msds are. Discover the effortless versatility of an instrument that makes it easy to handle any sample matrix, any interference, and any particle size. Designed to bring the benefits of ms chemical analysis to the field, the portability tm can service a. Before you can operate the finnigan mat252 mass spectrometer, you must have training. Figure 11 front view shows a system with a syringe pump, tu rbo v ion source, a diverter valve, and the optional nanospray ion source monitors.
Models 959 and 959d operations manual mass spectrometer. The max300lg delivers very fast data updates requiring minimal sample flow. The thermo scientific orbitrap idx tribrid mass spectrometer combines industryleading mass analyzer technology dedicated for small molecule analysis with the thermo scientific acquirex intelligent ms n data acquisition strategy, to collect more meaningful data. By capturing more lowabundance analytes and leveraging streamlined data analysis and mass spectral prediction tools, the systems.
Spectrometer do not change settings are optimized for selected. Mobile cart for transpector cpm compact process monitor analytical mass spectrometer gas analysis systems. Exactive operating manual thermo fisher scientific. Mass spectrometer operators guide 34 maple street milford, ma 01757 71500104102 revision b. Worldleading combination of mass accuracy, resolution, and sensitivity smartformula is the unique combination of accurate mass with true isotopic pattern tip automated determination of elemental composition, the formula finder footprint 640 x 640 mm, height 1220 mm, weight kg tof analyzer. The instruments used in such studies are called mass spectrometers and mass spectographs. Stanford university stable isotope laboratory online manual prepared by david a. Welcome to the thermo electron, finnigan tsq quantum ultra system. Unrivaled utility and flexibility most laboratories require the ability to analyze a range of samples using more than one technique for more complete identification and characterization of samples. A highly flexible researchgrade maldi toftof mass spectrometer essential features providing confident results highresolution ms data in reflectron mode for more accurate and confident peptide. The first commercialization of malditof ms by shimadzu began in 1988 with the launch of the lams50k. This manual contains the instructions required to start up and operate the. The microflex ltsh malditof mass spectrometer with n 2 laser at 60 hz repetition rate the microflex ltsh smart system with brukers proprietary smartbeam solidstate laser technology at 200 hz repetition rate, the first malditof system for microbial identification using a lifetime laser.
Our wide range of powerful, versatile, and proven mass spectrometrybased solutions deliver a new level of. Operation manual draft 42315 vacuum products division vs series helium mass spectrometer leak detectors models. This tsq quantum ultra getting started manual provides you with information on how to set up, calibrate, and tune the tsq quantum ultra tsq quantum ultra. The thermo scientific orbitrap idx tribrid mass spectrometer combines industryleading mass analyzer technology dedicated for small molecule analysis with the thermo scientific acquirex intelligent ms n. Bruker 7tsolarix icr ftms mass spectrometry center. Thermo scientific isq ec preinstallation manual pdf. In addition, this manual provi des stepbystep instruct ions for cleaning and maintaining your instrument. This overview and maintenance guide for the synapt xs covers preparing the mass spectrometer for operation, changing the mode of. About this manual this guide contains detailed instructions to prepare your site for installation of a thermo scientific isq ec or a thermo scientific isq em mass spectrometer. Small enough to be carried by one person, the portability tm is compatible with insitu. Whenever the safety protection of the instrument has been.
The portability tm mass spectrometer is one of bayspecs newest portable instruments. Figure 11 front view shows a system with a syringe pump, tu rbo v ion. Chemical ionization timeofflight mass spectrometer tof. Suitable protection against biohazards must be taken during maintenance procedures and.
The total mass range is defined by the calculated mass of the oligonucleotide and the user selected total mass tolerance. Whenever the safety protection of the instrument has been compromised, disconnect the. The following sections are a list of possible causes of the above conditions. Thermo scientific isq ec preinstallation manual pdf download. Thermo scientific tsq 8000 evo user manual pdf download.
Mass resolution up to 2,500,000 mass range up to 10,000 mz ecd, etd electron transfercapture dissociation and cid tools for structural analysis of proteins e. This primer covers a wide range of topics related to modern mass spectrometry practices and answers some frequently asked questions about the use and. View and download thermo scientific tsq 8000 evo user manual online. Ltq orbitrap series preinstallation requirements guide orbitrap velos pro getting. This was not only the first commercially available malditof mass spectrometer, but also. Chemical ionization is available for the turbo pump msds only.
Waters xevo tqxs mass overview and maintenance manual pdf. Chemical ionization timeofflight mass spectrometer tofcims the aerodyne tofcims combines chemical ionization with highresolution timeofflight mass spectrometry for sensitive, realtime identification and quantification of gasphase compounds in sampled air. With the aid of fieldaxis technology, the ions are able to cross the peripheral fields of the separating system without any noteworthy interaction. For consistent accuracy and precise results, you can rely on the inficon qmg 700 and our worldwide applications expertise. Tandem mass spectrometry is a technique that utilizes more than one mass selective stage in a mass spectrometer. Q exactive hybrid quadrupoleorbitrap mass spectrometer support. In this manual this manual describes the operation, troubleshooting, and maintenance of the agilent technologies 5973 network mass selective detector 5973n msd 1069huvlrq 5973n msds are equipped with either a diffusion pump or one of two turbomolecular turbo pumps. Q exactive hybrid quadrupoleorbitrap ms with zipchip system. Residual gas analyzers rga and mass spectrometers inficon. A quadrupole mass spectrometer skoog, holler, and crouch, 2007 the quadrupole mass spectrometer figure 6 is the most common type of mass spectrometer used in atomic mass.
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